The Effects of Cocaine on the Brain


Effects of cocaine to the brain Both cocaine and crack cocaine can cause damage the Brain and even if not used often.

Damage to brain structures can trigger addiction, which is a disease involving the

reward circuits and dopamine systems.
Excess consumption of this drug can cause other kinds of long-term damage as well.

Effects of cocaine to the brain

Mood, Emotions, and Mental Health

Powdered cocaine and  crack can cause long-term damage to mental health,

Because the drug directly interferes with dopamine being reabsorbed by neurons,

one of the symptoms of a cocaine comedown is serious depression

Other serious long-term changes to mood and mental health include:

Auditory hallucinations


Those who have an increased potential to develop psychosis or schizophrenia are more likely to provoke this condition if they consume cocaine in powdered or freebase form.

Physical Brain Changes

One of the most serious long-term effects from cocaine abuse is damage to the cardiovascular system.

This can lead to damage to many other organ systems, including the brain.People who struggle with cocaine addiction also show reduced levels of glucose

metabolism in many areas of the brain, suggesting that neurons under perform or begin to die.

Effects of cocaine to the brain And Aging

A recent study through the University of Cambridge examined the aging of the brain in people who abused cocaine and those who had no previous history of substance abuse. The group found that the average brain normally loses 1.69

milliliters of gray matter per year;  however, addicts in the past, or who were currently cocaine-dependent, doubled the rate of gray matter loss, for an average of 3.08 milliliters per year. Effects of cocaine to the brain




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